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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14c28f8b70a7e4b48f35e62fc7899159f991cb4cdc16200a4300c93e517adc58' 
  AND token = 'BuZfESJLVQFWxHXR9VrXKzWrKc9C3I9oTmDCLlY2AlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}