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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f34331d0ce1cfa0a6a11dde5f868e7edf5cf41ab1f2400f85b678f18bad16705' 
  AND token = 'vtF8JDbCHN11h3yPrm1xPki/Ht41hZoybbdoTrl+Wpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}