SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '843ea9f5fca999aefe74f05bc8b7cda9df7cc24225bcdce85f37e6c2a6806a52' 
  AND token = 'iEernxuZvEKC4iLrPJX3damOPdai5dAG5KA7udKiZ78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}