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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74266a1f300dc07868d8892a5563e2db2c701edadf3a0ee954c74f01f68c6426' 
  AND token = 'OehQQyIKG5HIDiC6pk/lodhagdaa2CMXoGSKOycq8DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}