SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef3ff54b9343d626d7181b178e45d7f6b10a261711af8a594a66cd06a35f5151' 
  AND token = 'J2o0cIkC7npHO+jTNVjgtmeGm31kCVrSGmIk0fedFZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}