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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99fcb43254ed21fa4d8a4f6ec4c6639b3e1f78cf37fc02bbe9e2b312d9b79ca4' 
  AND token = '1TVC3DxH+V+FWMlJYG2iQZR1coAo7VfsUK4IJIeBo5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}