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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '469190ba2bea3ed937ae0c35b26ce6b88ef7ded2f60aadd7570b162a1441f0ea' 
  AND token = 'tM+sHrsJx3hwpuWn/Ess+WTUzv5mPuiKEyHLjYXMa7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}