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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01d2cb50f6ca03ffcdd8fa6cd11746b09de9968a18fddb4f3e5f93bc425e414' 
  AND token = 'G47F1pe3O7rl9fqBsMsWgb+PeB4vRwO2OB6qesJ2oOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}