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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e21621eed057800d48a3c134fe0e7afbe218e80db6dad3886fa9832c3d211ca' 
  AND token = 'Nf7hZIQqKpY6f0K7jt3bEbjewuvBSnm7Lm6psO/H6lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}