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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25a3f3c46409036f906de1f272d180d82bc29bc91ef81b4ec678cce91fe55dd' 
  AND token = '7fmshm449MKk3OQ44GDlQ+UC1KdUbb5k+qOsuU/Xpkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}