SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8593b943f85e817188585189c5d77db0839c3d6f037acd701e00cbcb59b87860' 
  AND token = 'F22dh2OXbuP80Zc8SDvxtNnao9LKFQRUQ40FLXpuHoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}