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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '614d59051f743d9940b38bb8525bcd40510a8b58d31789cba77469196b027510' 
  AND token = 'oiTur1+ScxamMNCpZ84KpFq1Y1pMTzPqWuRINKJHysU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}