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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45611efe8ab3a426385b270692591194232e91db4d6bed67093b2cbd6fae5c00' 
  AND token = 'LqhcCZP9YTzZ6cYaAgd9prXQ2q573CB1RsAEgwPrpIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}