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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1c372e00bf9e7dd1fd2e41bbf2b8bf0f393a001b49c443707bf1a077fdd2d9c' 
  AND token = 'uAUpnLu5k4gyOatZ0IKqM0KB/4hoZgWXHnodtJmTg8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}