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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4314670e2f3560589eb39eebace8529d9e3ed4fe1fb0c96516ef30d66ed0d964' 
  AND token = 'F1AmDy0mYR92FbeHXJIRsXhsYYtU5Va/9v8o64abw9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}