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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb54b62b0e8370f6b7fe9841f7ece4c3b7cc031f7830601e0568faede04e469' 
  AND token = 'z+Pndr/xi51fRWqXC1RFNERgKbM8x5zF8j8U9U1vb9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}