SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c885a1a69c6964863060f63d3124ebbb89cc8de9e66bdcf24c0239eb88e53e93' 
  AND token = 'EIrTsepuaAUGxuqg66DXoJPZwlJP3d6hUpD3erWCYFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}