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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73adad3aec1699a358e589f77393f18f937116ae9831a6d83361e140d37aeafd' 
  AND token = '+Y9wVoc7+A7bGcMIUv+feTEgp5hTyHzPEiBmjXHMIls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}