SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b63e1fb4516ee95a909e311f6e214e3c3642aefc8f787005f6d3f4f80225bd' 
  AND token = 'anSwcmyfiRC3LaoZ4R43VVuNzzsixUo6pa2vDf0fVho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}