SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ab23373e0c1ff7b15345f347018c83055442e46231105e443389e10e17d0c7e' 
  AND token = '6VmNUSuV6VyCkgSxhIEfiygonrwqrqRr+Z/BgZCRgEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}