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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b29186380caa4cf4a9b48e54fd60b720f98dceaa03f3b8ac329a3092d332889' 
  AND token = 'jjMU3U4IImm2HHBriwkkvNdRnDv9ndk2zWcHmhGVtLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}