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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f211be63b92e5f80081000ec14b3c4bc63b1269c3ad0fe0e77c87f36e073266' 
  AND token = 'JsvlNEcqeh25WOfjl1sn6V/8vAmVafk5uQhF3U9BwVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}