SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82bdb6fa56c882c8d1cbc5a2505414060204bda0beaff109e971aca5a884e3d8' 
  AND token = 'EnVdsReVIp4z1nKuid+j8L2+gh9z+Xi8Bd7HNNBDmy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}