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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1204dbda899cabd8ff0b1e0fab9666522a44c46b09a1d73cedb43170cf8ffc0' 
  AND token = '2n+UMh1cKmXjL7SF9Xq6TcSlOj+frWCRzeWXhKC6o+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}