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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a18ea613936f6ddc79ee1224c6c1ff0e35306895aa4443e65cf264587b77f9af' 
  AND token = '0/fxIWbDWdpGZGaFFGDMmmqIgEgNCo50UKZa6tRN38g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}