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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a4a97563662aeb880b3bd71ea02f754cae9cdc5bab39727e85e1446a12a85e6' 
  AND token = 'DLQ74P2rNr3Vuilmn9Eg7uwze4mzgTEXVQBj01PHZQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}