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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42da27baeeac31cb7adddff08b5397ce97cb436d92de4dbcca09586692e03a8' 
  AND token = 'D+AniDrmrbTl5QOK1oN92S6kifHxOtRUJGXY2spx4M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}