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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8754ca76b2137f5783d01600498b45cad82ddb4de909d6f250b0d9107aa71e3' 
  AND token = 'nQyVKU70wIHet9Gq2m8ffD4+JAXHGnVm0PxFzF0qMl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}