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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a708c781464e9d40bf265d58e4cca10341cef2f2c6ee410da01835c0414fd4' 
  AND token = 'ynHNMyN5GwBxLQMMmjM3H58Dud7K/1UVe5ulTQYu4xU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}