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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7c492c7adcd56c786e0346b5ad373bede26c33b8c0e7e3e899a8502c0fdd27d' 
  AND token = 'DoE1k5GrEwfxXMZ69IuN7OfNBoJrY2uvxXipUqpxaB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}