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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb9f276ca2733523ffd19f282ad79f58e2566f670345068557767b50e252a2fc' 
  AND token = '44HPAKhDy2/sQUxppFD8amv9pdT5hyQWLQQaCKYM8A8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}