SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02df12305fded01d969186d584a1fae92e28e690b59d124fe0603e1e8a8850ec' 
  AND token = 'DnIo/weDFER1N1MfMWaKy6kh7Q0eIyLWCSiahC/CUYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}