SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043e244bbe78114002c9a111a67b67ad58685487e87d4a7f1210e3685803f77f' 
  AND token = 'M7QbXe3u+ZLm6+G2WJ4tK0sGVaZ0o+td4+s80xlZ82I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}