SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d61505c207fba1cb20a4e8c6e2a3810df13eca9817deee92b1c5aec45fac9ef' 
  AND token = 'U48mVlnZ9sMAWCR5dCGxPaU7IvVjQ7HG1O4xaurA0vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}