SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac9d09cb41f43c0fbbe9f8963129d811a09babb8c0cdadd60d00e2e6663d66f1' 
  AND token = 'lU1FX57Y1dPSaxsejOA0NWSKQZdE7VS2xztJ5AHwd5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}