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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c40a8424e3e0e97a6e0b097d7d51411b0a577aac38f7e34fdbb9df3cf4adb67' 
  AND token = 'uCNaq/mbIa0WnGRuaFtVFTTjYngaLm5yS28mTlUr8Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}