SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37d902a06bc529970bcfc6ef3095edc1e999b3da12e64bf568732d4148c36589' 
  AND token = 'VQISs6EJ7WqVzfQk4F+6KP+D8q+zAWyMhO7sNmYZsVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}