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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acac3ee5dbc3b99b54e8bdebc4f3552f70a3f212787db3414dc5f3edae0b0472' 
  AND token = 'RwRZ8pO3YrZY3X/ErduFShv7MQDwhEqbgueKHZNAUqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}