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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8bf05f26896f0a447c5cdeb23943b41b9818fcf2b9d4084b7d77bf426dc290d' 
  AND token = 'UOaKq2cYKOOpqqdUzYpvdwdki6b0V131m6mOrGVUH+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}