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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f00bf042cb29b08a52d83f1986bdc4a559b8572593d35c570058e9a30d22f71a' 
  AND token = 'GrL/obq7qi3LUUkCF65SLFgXVqGQpSF/8oiVTpZmfTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}