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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ae64a5abe15d024b0d653590ed96d38d898493b02936eb806b687d13bed506e' 
  AND token = 'vc9OVTt8pfbELct1BygavrPMBlg+XCVfeMuzYkxhA8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}