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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '504e63edf2701a6b6fc8c6fc7e9d93fd9f34e4da63b50debe321a4a8b57b9923' 
  AND token = '5045rXbK5CgjzpmmfjkwdQXnmo3KFyzgPE3qKbTaT3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}