SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e849c8c4135fd8892a78a337280edb8dc86b69f810ba6350fc23b0a921db916f' 
  AND token = 'pdEV8R2Jk4P3jTZby3MXY6zgDNZ/MmNN6zO7zqoamWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}