SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f07cfec546bd94b7cfb16d87c6a0df4aaec22fdd1c0509451a186d27f75a075' 
  AND token = '/Jb+0JSijUtOyIgP7EXfHs+7Y4Rrd6dyo6q4gbqWLRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}