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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '235345e2e5194b8c73cffa077ae6ed1b9f8c497615be0a2d1d08cd12d870f8c6' 
  AND token = 'FiDzds5zmcXlrQVcFXcerk75CVZD+gvl1v5tsgG+DuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}