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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '842b81fca1fa7ab4775420a7c78e87f7f4d4bd6514ef1a9ca1118183fee1f9d7' 
  AND token = '/iXhJWOIU+6JPkDdK3j0ej0Emvn+WmhwixDlmbLOlAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}