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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d66cd1eb97d09bc4b528514bdf303ee799c9dc3b6ee5081c85c403d5bca2b2' 
  AND token = 'DNtYBBi37LbpDEN9F5VkJnZwvPZ7s2E1v9V/92TPWo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}