SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a34f75d8be335001a365ff3bffbd69308cd5a2903ef5bbad53ee9bf962687426' 
  AND token = 'qGKDcIRv7MNkfK84Zd9GMvx3ZfSJ9UPODRzoCb3kzuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}