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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bd3efbedd8a20f28bdbc01beb472fe5a58810e0d5e843775add16471be8d586' 
  AND token = 'e/2xuU2cxfLszT8kp5RyXc85FLkI9HGeG+54S/622Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}