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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13e0c245adb2e398756e4621b7c7ada2811c9e951dc094d25a331dffa346beb6' 
  AND token = 'IvmLzd23EyQTpDJLHvzAwg+d0qt3C9BMzq8sORe0CwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}